Inactivation of Fam20B in Joint Cartilage Leads to Chondrosarcoma and Postnatal Ossification Defects

During endochondral ossification, chondrocytes embed themselves in a proteoglycan-rich matrix during the proliferation-maturation transition. Accumulating evidence shows that proteoglycans are essential components for chondrocyte proliferation and differentiation. When we conditionally inactivated F...

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Detalles Bibliográficos
Autores principales: Ma, Pan, Yan, Wenjuan, Tian, Ye, Wang, Jingya, Feng, Jian Q., Qin, Chunlin, Cheng, Yi-Shing Lisa, Wang, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942823/
https://www.ncbi.nlm.nih.gov/pubmed/27405802
http://dx.doi.org/10.1038/srep29814

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