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Tunable switch mediated shikimate biosynthesis in an engineered non-auxotrophic Escherichia coli
Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942831/ https://www.ncbi.nlm.nih.gov/pubmed/27406890 http://dx.doi.org/10.1038/srep29745 |