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Tunable switch mediated shikimate biosynthesis in an engineered non-auxotrophic Escherichia coli

Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shi...

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Detalles Bibliográficos
Autores principales: Gu, Pengfei, Su, Tianyuan, Wang, Qian, Liang, Quanfeng, Qi, Qingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942831/
https://www.ncbi.nlm.nih.gov/pubmed/27406890
http://dx.doi.org/10.1038/srep29745