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Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice
BACKGROUND: Changes to the epigenome with aging, and DNA modifications in particular, have been proposed as a central regulator of the aging process, a predictor of mortality, and a contributor to the pathogenesis of age-related diseases. In the central nervous system, control of learning and memory...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942942/ https://www.ncbi.nlm.nih.gov/pubmed/27413395 http://dx.doi.org/10.1186/s13072-016-0080-6 |