Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice

BACKGROUND: Changes to the epigenome with aging, and DNA modifications in particular, have been proposed as a central regulator of the aging process, a predictor of mortality, and a contributor to the pathogenesis of age-related diseases. In the central nervous system, control of learning and memory...

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Detalles Bibliográficos
Autores principales: Hadad, Niran, Masser, Dustin R., Logan, Sreemathi, Wronowski, Benjamin, Mangold, Colleen A., Clark, Nicholas, Otalora, Laura, Unnikrishnan, Archana, Ford, Matthew M., Giles, Cory B., Wren, Jonathan D., Richardson, Arlan, Sonntag, William E., Stanford, David R., Freeman, Willard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942942/
https://www.ncbi.nlm.nih.gov/pubmed/27413395
http://dx.doi.org/10.1186/s13072-016-0080-6

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