Germinal center B cells recognize antigen through a specialized immune synapse architecture

B cell activation is regulated by B cell antigen receptor (BCR) signaling and antigen internalization in immune synapses. Using large-scale imaging across B cell subsets, we show that in contrast to naive and memory B cells, which gathered antigen towards the synapse center before internalization, g...

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Detalles Bibliográficos
Autores principales: Nowosad, Carla R., Spillane, Katelyn M., Tolar, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943528/
https://www.ncbi.nlm.nih.gov/pubmed/27183103
http://dx.doi.org/10.1038/ni.3458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943528/
https://www.ncbi.nlm.nih.gov/pubmed/27183103
http://dx.doi.org/10.1038/ni.3458

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