Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus

Hepatosteatosis is highly prevalent among patients living with human immunodeficiency virus. In a 1-year, randomized, double-blind trial of atorvastatin or placebo, atorvastatin increased liver/spleen ratio among patients with nonalcoholic fatty liver disease, indicating a reduction in hepatosteatos...

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Detalles Bibliográficos
Autores principales: Lo, Janet, Lu, Michael T., Kim, Elli A., Nou, Eric, Hallett, Travis R., Park, Jakob, Hoffmann, Udo, Grinspoon, Steven K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943550/
https://www.ncbi.nlm.nih.gov/pubmed/27419149
http://dx.doi.org/10.1093/ofid/ofw062
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author Lo, Janet
Lu, Michael T.
Kim, Elli A.
Nou, Eric
Hallett, Travis R.
Park, Jakob
Hoffmann, Udo
Grinspoon, Steven K.
author_facet Lo, Janet
Lu, Michael T.
Kim, Elli A.
Nou, Eric
Hallett, Travis R.
Park, Jakob
Hoffmann, Udo
Grinspoon, Steven K.
author_sort Lo, Janet
collection PubMed
description Hepatosteatosis is highly prevalent among patients living with human immunodeficiency virus. In a 1-year, randomized, double-blind trial of atorvastatin or placebo, atorvastatin increased liver/spleen ratio among patients with nonalcoholic fatty liver disease, indicating a reduction in hepatosteatosis. This reduction in hepatosteatosis is associated with reduction in low-density lipoprotein cholesterol with statin therapy.
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spelling pubmed-49435502016-07-14 Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus Lo, Janet Lu, Michael T. Kim, Elli A. Nou, Eric Hallett, Travis R. Park, Jakob Hoffmann, Udo Grinspoon, Steven K. Open Forum Infect Dis Brief Reports Hepatosteatosis is highly prevalent among patients living with human immunodeficiency virus. In a 1-year, randomized, double-blind trial of atorvastatin or placebo, atorvastatin increased liver/spleen ratio among patients with nonalcoholic fatty liver disease, indicating a reduction in hepatosteatosis. This reduction in hepatosteatosis is associated with reduction in low-density lipoprotein cholesterol with statin therapy. Oxford University Press 2016-06-13 /pmc/articles/PMC4943550/ /pubmed/27419149 http://dx.doi.org/10.1093/ofid/ofw062 Text en © The Author 2016. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Lo, Janet
Lu, Michael T.
Kim, Elli A.
Nou, Eric
Hallett, Travis R.
Park, Jakob
Hoffmann, Udo
Grinspoon, Steven K.
Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus
title Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus
title_full Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus
title_fullStr Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus
title_full_unstemmed Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus
title_short Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus
title_sort statin effects to reduce hepatosteatosis as measured by computed tomography in patients with human immunodeficiency virus
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943550/
https://www.ncbi.nlm.nih.gov/pubmed/27419149
http://dx.doi.org/10.1093/ofid/ofw062
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