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Inhibition of Midkine Augments Osteoporotic Fracture Healing
The heparin-binding growth and differentiation factor midkine (Mdk) is proposed to negatively regulate osteoblast activity and bone formation in the adult skeleton. As Mdk-deficient mice were protected from ovariectomy (OVX)-induced bone loss, this factor may also play a role in the pathogenesis of...
Autores principales: | Haffner-Luntzer, Melanie, Kemmler, Julia, Heidler, Verena, Prystaz, Katja, Schinke, Thorsten, Amling, Michael, Kovtun, Anna, Rapp, Anna E., Ignatius, Anita, Liedert, Astrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943649/ https://www.ncbi.nlm.nih.gov/pubmed/27410432 http://dx.doi.org/10.1371/journal.pone.0159278 |
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