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Esophageal eosinophilia in pediatric patients with cerebral palsy

OBJECTIVE: To describe the clinical picture, test results, and clinical evolution of patients with cerebral palsy associated with diagnosis of eosinophilic esophagitis, monitored at tertiary centre. METHODS: Cross-sectional, retrospective and descriptive study that evaluated the medical records data...

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Autores principales: de Nápolis, Ana Carolina Ramos, Alves, Flavia Araujo, Rezende, Erica Rodrigues Mariano de Almeida, Segundo, Gesmar Rodrigues Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Ensino e Pesquisa Albert Einstein 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943815/
https://www.ncbi.nlm.nih.gov/pubmed/26154544
http://dx.doi.org/10.1590/S1679-45082015AO3266
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author de Nápolis, Ana Carolina Ramos
Alves, Flavia Araujo
Rezende, Erica Rodrigues Mariano de Almeida
Segundo, Gesmar Rodrigues Silva
author_facet de Nápolis, Ana Carolina Ramos
Alves, Flavia Araujo
Rezende, Erica Rodrigues Mariano de Almeida
Segundo, Gesmar Rodrigues Silva
author_sort de Nápolis, Ana Carolina Ramos
collection PubMed
description OBJECTIVE: To describe the clinical picture, test results, and clinical evolution of patients with cerebral palsy associated with diagnosis of eosinophilic esophagitis, monitored at tertiary centre. METHODS: Cross-sectional, retrospective and descriptive study that evaluated the medical records data of pediatric patients with diagnosis of cerebral palsy and eosinophilic esophagitis in a tertiary center of pediatric gastroenterology between August 2005 and August 2013. RESULTS: Seven out of 131 patients with cerebral palsy had the diagnosis of eosinophilic esophagitis. The mean age at diagnosis of eosinophilic esophagitis was 52.3 months and the mean number of eosinophils in esophagus was 35 per high-power field. Symptoms more frequent were recurrent vomiting and disphagia. Endoscopic alterations found were mucosal thickening, vertical lines, mucosal opacificacion and white plaques. CONCLUSION: The frequency of eosinophilic esophagitis found was higher than in general pediatric population. The investigation of eosinophilic esophagitis should be done regularly in those patients, once this entity could overlap other gastrointestinal diseases.
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spelling pubmed-49438152016-08-10 Esophageal eosinophilia in pediatric patients with cerebral palsy de Nápolis, Ana Carolina Ramos Alves, Flavia Araujo Rezende, Erica Rodrigues Mariano de Almeida Segundo, Gesmar Rodrigues Silva Einstein (Sao Paulo) Original Article OBJECTIVE: To describe the clinical picture, test results, and clinical evolution of patients with cerebral palsy associated with diagnosis of eosinophilic esophagitis, monitored at tertiary centre. METHODS: Cross-sectional, retrospective and descriptive study that evaluated the medical records data of pediatric patients with diagnosis of cerebral palsy and eosinophilic esophagitis in a tertiary center of pediatric gastroenterology between August 2005 and August 2013. RESULTS: Seven out of 131 patients with cerebral palsy had the diagnosis of eosinophilic esophagitis. The mean age at diagnosis of eosinophilic esophagitis was 52.3 months and the mean number of eosinophils in esophagus was 35 per high-power field. Symptoms more frequent were recurrent vomiting and disphagia. Endoscopic alterations found were mucosal thickening, vertical lines, mucosal opacificacion and white plaques. CONCLUSION: The frequency of eosinophilic esophagitis found was higher than in general pediatric population. The investigation of eosinophilic esophagitis should be done regularly in those patients, once this entity could overlap other gastrointestinal diseases. Instituto de Ensino e Pesquisa Albert Einstein 2015 /pmc/articles/PMC4943815/ /pubmed/26154544 http://dx.doi.org/10.1590/S1679-45082015AO3266 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
de Nápolis, Ana Carolina Ramos
Alves, Flavia Araujo
Rezende, Erica Rodrigues Mariano de Almeida
Segundo, Gesmar Rodrigues Silva
Esophageal eosinophilia in pediatric patients with cerebral palsy
title Esophageal eosinophilia in pediatric patients with cerebral palsy
title_full Esophageal eosinophilia in pediatric patients with cerebral palsy
title_fullStr Esophageal eosinophilia in pediatric patients with cerebral palsy
title_full_unstemmed Esophageal eosinophilia in pediatric patients with cerebral palsy
title_short Esophageal eosinophilia in pediatric patients with cerebral palsy
title_sort esophageal eosinophilia in pediatric patients with cerebral palsy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943815/
https://www.ncbi.nlm.nih.gov/pubmed/26154544
http://dx.doi.org/10.1590/S1679-45082015AO3266
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