Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5

The hepatocyte nuclear factor 1β gene (HNF1B) is responsible for maturity-onset diabetes of the young type 5 (MODY5), which is characterized by early-onset diabetes mellitus and urogenital malformations. HNF1B is expressed during visceral endoderm formation. We identified a disruption of the great p...

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Autores principales: Iwasaki, Naoko, Tsurumi, Masashi, Asai, Kuniya, Shimuzu, Wataru, Watanabe, Atsushi, Ogata, Makiko, Takizawa, Miho, Ide, Risa, Yamamoto, Toshiyuki, Saito, Kayoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Data Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944010/
https://www.ncbi.nlm.nih.gov/pubmed/27468355
http://dx.doi.org/10.1038/hgv.2016.22
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author Iwasaki, Naoko
Tsurumi, Masashi
Asai, Kuniya
Shimuzu, Wataru
Watanabe, Atsushi
Ogata, Makiko
Takizawa, Miho
Ide, Risa
Yamamoto, Toshiyuki
Saito, Kayoko
author_facet Iwasaki, Naoko
Tsurumi, Masashi
Asai, Kuniya
Shimuzu, Wataru
Watanabe, Atsushi
Ogata, Makiko
Takizawa, Miho
Ide, Risa
Yamamoto, Toshiyuki
Saito, Kayoko
author_sort Iwasaki, Naoko
collection PubMed
description The hepatocyte nuclear factor 1β gene (HNF1B) is responsible for maturity-onset diabetes of the young type 5 (MODY5), which is characterized by early-onset diabetes mellitus and urogenital malformations. HNF1B is expressed during visceral endoderm formation. We identified a disruption of the great pancreatic artery in a patient with MODY5 with no pancreatic body or tail. Our finding supports the significance of HNF1B in the development of the pancreas.
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spelling pubmed-49440102016-07-27 Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5 Iwasaki, Naoko Tsurumi, Masashi Asai, Kuniya Shimuzu, Wataru Watanabe, Atsushi Ogata, Makiko Takizawa, Miho Ide, Risa Yamamoto, Toshiyuki Saito, Kayoko Hum Genome Var Data Report The hepatocyte nuclear factor 1β gene (HNF1B) is responsible for maturity-onset diabetes of the young type 5 (MODY5), which is characterized by early-onset diabetes mellitus and urogenital malformations. HNF1B is expressed during visceral endoderm formation. We identified a disruption of the great pancreatic artery in a patient with MODY5 with no pancreatic body or tail. Our finding supports the significance of HNF1B in the development of the pancreas. Nature Publishing Group 2016-07-14 /pmc/articles/PMC4944010/ /pubmed/27468355 http://dx.doi.org/10.1038/hgv.2016.22 Text en Copyright © 2016 The Author(s) 2016 http://creativecommons.org/licenses/by-nc-sa/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/
spellingShingle Data Report
Iwasaki, Naoko
Tsurumi, Masashi
Asai, Kuniya
Shimuzu, Wataru
Watanabe, Atsushi
Ogata, Makiko
Takizawa, Miho
Ide, Risa
Yamamoto, Toshiyuki
Saito, Kayoko
Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5
title Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5
title_full Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5
title_fullStr Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5
title_full_unstemmed Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5
title_short Pancreatic developmental defect evaluated by celiac artery angiography in a patient with MODY5
title_sort pancreatic developmental defect evaluated by celiac artery angiography in a patient with mody5
topic Data Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944010/
https://www.ncbi.nlm.nih.gov/pubmed/27468355
http://dx.doi.org/10.1038/hgv.2016.22
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