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Defective Glucose Metabolism in Polycystic Kidney Disease Identifies A Novel Therapeutic Paradigm
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disorder characterized by bilateral renal cyst formation(1). Recent identification of signaling cascades de-regulated in ADPKD has led to the initiation of several clinical trials, but an approved therapy is still lacking(2,3)....
Autores principales: | Rowe, Isaline, Chiaravalli, Marco, Mannella, Valeria, Ulisse, Valeria, Quilici, Giacomo, Pema, Monika, Song, Xuewen W., Xu, Hangxue, Mari, Silvia, Qian, Feng, Pei, York, Musco, Giovanna, Boletta, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944011/ https://www.ncbi.nlm.nih.gov/pubmed/23524344 http://dx.doi.org/10.1038/nm.3092 |
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