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A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125

The activity of RING ubiquitin ligases (E3s) depends on an interaction between the RING domain and ubiquitin conjugating enzymes (E2), but posttranslational events or additional structural elements, yet largely undefined, are frequently required to enhance or regulate activity. Here, we show for the...

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Detalles Bibliográficos
Autores principales: Bijlmakers, Marie-José, Teixeira, João M. C., Boer, Roeland, Mayzel, Maxim, Puig-Sàrries, Pilar, Karlsson, Göran, Coll, Miquel, Pons, Miquel, Crosas, Bernat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944129/
https://www.ncbi.nlm.nih.gov/pubmed/27411375
http://dx.doi.org/10.1038/srep29232

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