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An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept

Plasmacytoid dendritic cells (pDC) are specialized immune cells that produce massive levels of type I interferon in response to pathogens. Unfortunately, pDC are fragile and extremely rare, rendering their functional study a tough challenge. However, because of their central role in numerous patholo...

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Detalles Bibliográficos
Autores principales:	Smith, Nikaïa, Vidalain, Pierre-Olivier, Nisole, Sébastien, Herbeuval, Jean-Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944138/ https://www.ncbi.nlm.nih.gov/pubmed/27412723 http://dx.doi.org/10.1038/srep29891

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