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Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand

BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening dermatologic conditions. Although, the incidence of SJS/TEN in Thailand is high, information on cost of care for SJS/TEN is limited. This study aims to estimate healthcare resource utilization and co...

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Autores principales: Dilokthornsakul, P, Sawangjit, R, Inprasong, C, Chunhasewee, S, Rattanapan, P, Thoopputra, T, Chaiyakunapruk, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944341/
https://www.ncbi.nlm.nih.gov/pubmed/27089110
http://dx.doi.org/10.4103/0022-3859.180571
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author Dilokthornsakul, P
Sawangjit, R
Inprasong, C
Chunhasewee, S
Rattanapan, P
Thoopputra, T
Chaiyakunapruk, N
author_facet Dilokthornsakul, P
Sawangjit, R
Inprasong, C
Chunhasewee, S
Rattanapan, P
Thoopputra, T
Chaiyakunapruk, N
author_sort Dilokthornsakul, P
collection PubMed
description BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening dermatologic conditions. Although, the incidence of SJS/TEN in Thailand is high, information on cost of care for SJS/TEN is limited. This study aims to estimate healthcare resource utilization and cost of SJS/TEN in Thailand, using hospital perspective. METHODS: A retrospective study using an electronic health database from a university-affiliated hospital in Thailand was undertaken. Patients admitted with SJS/TEN from 2002 to 2007 were included. Direct medical cost was estimated by the cost-to-charge ratio. Cost was converted to 2013 value by consumer price index, and converted to $US using 31 Baht/1 $US. The healthcare resource utilization was also estimated. RESULTS: A total of 157 patients were included with average age of 45.3±23.0 years. About 146 patients (93.0%) were diagnosed as SJS and the remaining (7.0%) were diagnosed as TEN. Most of the patients (83.4%) were treated with systemic corticosteroids. Overall, mortality rate was 8.3%, while the average length of stay (LOS) was 10.1±13.2 days. The average cost of managing SJS/TEN for all patients was $1,064±$2,558. The average cost for SJS patients was $1,019±$2,601 while that for TEN patients was $1,660±$1,887. CONCLUSIONS: Healthcare resource utilization and cost of care for SJS/TEN in Thailand were tremendous. The findings are important for policy makers to allocate healthcare resources and develop strategies to prevent SJS/TEN which could decrease length of stay and cost of care.
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spelling pubmed-49443412016-07-25 Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand Dilokthornsakul, P Sawangjit, R Inprasong, C Chunhasewee, S Rattanapan, P Thoopputra, T Chaiyakunapruk, N J Postgrad Med Economic Evaluation BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening dermatologic conditions. Although, the incidence of SJS/TEN in Thailand is high, information on cost of care for SJS/TEN is limited. This study aims to estimate healthcare resource utilization and cost of SJS/TEN in Thailand, using hospital perspective. METHODS: A retrospective study using an electronic health database from a university-affiliated hospital in Thailand was undertaken. Patients admitted with SJS/TEN from 2002 to 2007 were included. Direct medical cost was estimated by the cost-to-charge ratio. Cost was converted to 2013 value by consumer price index, and converted to $US using 31 Baht/1 $US. The healthcare resource utilization was also estimated. RESULTS: A total of 157 patients were included with average age of 45.3±23.0 years. About 146 patients (93.0%) were diagnosed as SJS and the remaining (7.0%) were diagnosed as TEN. Most of the patients (83.4%) were treated with systemic corticosteroids. Overall, mortality rate was 8.3%, while the average length of stay (LOS) was 10.1±13.2 days. The average cost of managing SJS/TEN for all patients was $1,064±$2,558. The average cost for SJS patients was $1,019±$2,601 while that for TEN patients was $1,660±$1,887. CONCLUSIONS: Healthcare resource utilization and cost of care for SJS/TEN in Thailand were tremendous. The findings are important for policy makers to allocate healthcare resources and develop strategies to prevent SJS/TEN which could decrease length of stay and cost of care. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4944341/ /pubmed/27089110 http://dx.doi.org/10.4103/0022-3859.180571 Text en Copyright: © 2016 Journal of Postgraduate Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Economic Evaluation
Dilokthornsakul, P
Sawangjit, R
Inprasong, C
Chunhasewee, S
Rattanapan, P
Thoopputra, T
Chaiyakunapruk, N
Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand
title Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand
title_full Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand
title_fullStr Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand
title_full_unstemmed Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand
title_short Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand
title_sort healthcare utilization and cost of stevens-johnson syndrome and toxic epidermal necrolysis management in thailand
topic Economic Evaluation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944341/
https://www.ncbi.nlm.nih.gov/pubmed/27089110
http://dx.doi.org/10.4103/0022-3859.180571
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