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Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand
BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening dermatologic conditions. Although, the incidence of SJS/TEN in Thailand is high, information on cost of care for SJS/TEN is limited. This study aims to estimate healthcare resource utilization and co...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944341/ https://www.ncbi.nlm.nih.gov/pubmed/27089110 http://dx.doi.org/10.4103/0022-3859.180571 |
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author | Dilokthornsakul, P Sawangjit, R Inprasong, C Chunhasewee, S Rattanapan, P Thoopputra, T Chaiyakunapruk, N |
author_facet | Dilokthornsakul, P Sawangjit, R Inprasong, C Chunhasewee, S Rattanapan, P Thoopputra, T Chaiyakunapruk, N |
author_sort | Dilokthornsakul, P |
collection | PubMed |
description | BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening dermatologic conditions. Although, the incidence of SJS/TEN in Thailand is high, information on cost of care for SJS/TEN is limited. This study aims to estimate healthcare resource utilization and cost of SJS/TEN in Thailand, using hospital perspective. METHODS: A retrospective study using an electronic health database from a university-affiliated hospital in Thailand was undertaken. Patients admitted with SJS/TEN from 2002 to 2007 were included. Direct medical cost was estimated by the cost-to-charge ratio. Cost was converted to 2013 value by consumer price index, and converted to $US using 31 Baht/1 $US. The healthcare resource utilization was also estimated. RESULTS: A total of 157 patients were included with average age of 45.3±23.0 years. About 146 patients (93.0%) were diagnosed as SJS and the remaining (7.0%) were diagnosed as TEN. Most of the patients (83.4%) were treated with systemic corticosteroids. Overall, mortality rate was 8.3%, while the average length of stay (LOS) was 10.1±13.2 days. The average cost of managing SJS/TEN for all patients was $1,064±$2,558. The average cost for SJS patients was $1,019±$2,601 while that for TEN patients was $1,660±$1,887. CONCLUSIONS: Healthcare resource utilization and cost of care for SJS/TEN in Thailand were tremendous. The findings are important for policy makers to allocate healthcare resources and develop strategies to prevent SJS/TEN which could decrease length of stay and cost of care. |
format | Online Article Text |
id | pubmed-4944341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-49443412016-07-25 Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand Dilokthornsakul, P Sawangjit, R Inprasong, C Chunhasewee, S Rattanapan, P Thoopputra, T Chaiyakunapruk, N J Postgrad Med Economic Evaluation BACKGROUND: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening dermatologic conditions. Although, the incidence of SJS/TEN in Thailand is high, information on cost of care for SJS/TEN is limited. This study aims to estimate healthcare resource utilization and cost of SJS/TEN in Thailand, using hospital perspective. METHODS: A retrospective study using an electronic health database from a university-affiliated hospital in Thailand was undertaken. Patients admitted with SJS/TEN from 2002 to 2007 were included. Direct medical cost was estimated by the cost-to-charge ratio. Cost was converted to 2013 value by consumer price index, and converted to $US using 31 Baht/1 $US. The healthcare resource utilization was also estimated. RESULTS: A total of 157 patients were included with average age of 45.3±23.0 years. About 146 patients (93.0%) were diagnosed as SJS and the remaining (7.0%) were diagnosed as TEN. Most of the patients (83.4%) were treated with systemic corticosteroids. Overall, mortality rate was 8.3%, while the average length of stay (LOS) was 10.1±13.2 days. The average cost of managing SJS/TEN for all patients was $1,064±$2,558. The average cost for SJS patients was $1,019±$2,601 while that for TEN patients was $1,660±$1,887. CONCLUSIONS: Healthcare resource utilization and cost of care for SJS/TEN in Thailand were tremendous. The findings are important for policy makers to allocate healthcare resources and develop strategies to prevent SJS/TEN which could decrease length of stay and cost of care. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4944341/ /pubmed/27089110 http://dx.doi.org/10.4103/0022-3859.180571 Text en Copyright: © 2016 Journal of Postgraduate Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Economic Evaluation Dilokthornsakul, P Sawangjit, R Inprasong, C Chunhasewee, S Rattanapan, P Thoopputra, T Chaiyakunapruk, N Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand |
title | Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand |
title_full | Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand |
title_fullStr | Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand |
title_full_unstemmed | Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand |
title_short | Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand |
title_sort | healthcare utilization and cost of stevens-johnson syndrome and toxic epidermal necrolysis management in thailand |
topic | Economic Evaluation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944341/ https://www.ncbi.nlm.nih.gov/pubmed/27089110 http://dx.doi.org/10.4103/0022-3859.180571 |
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