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Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study

BACKGROUND: Older people frequently attend the emergency department (ED) and have a high risk of poor outcome as compared to their younger counterparts. Our aim was to study routinely collected clinical parameters as predictors of 90-day mortality in older patients attending our ED. METHODS: We cond...

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Autores principales: Hofman, Susanna E., Lucke, Jacinta A., Heim, Noor, de Gelder, Jelle, Fogteloo, Anne J., Heringhaus, Christian, de Groot, Bas, de Craen, Anton J. M., Blauw, Gerard Jan, Mooijaart, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944462/
https://www.ncbi.nlm.nih.gov/pubmed/27412243
http://dx.doi.org/10.1186/s12873-016-0090-5
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author Hofman, Susanna E.
Lucke, Jacinta A.
Heim, Noor
de Gelder, Jelle
Fogteloo, Anne J.
Heringhaus, Christian
de Groot, Bas
de Craen, Anton J. M.
Blauw, Gerard Jan
Mooijaart, Simon P.
author_facet Hofman, Susanna E.
Lucke, Jacinta A.
Heim, Noor
de Gelder, Jelle
Fogteloo, Anne J.
Heringhaus, Christian
de Groot, Bas
de Craen, Anton J. M.
Blauw, Gerard Jan
Mooijaart, Simon P.
author_sort Hofman, Susanna E.
collection PubMed
description BACKGROUND: Older people frequently attend the emergency department (ED) and have a high risk of poor outcome as compared to their younger counterparts. Our aim was to study routinely collected clinical parameters as predictors of 90-day mortality in older patients attending our ED. METHODS: We conducted a retrospective follow-up study at the Leiden University Medical Center (The Netherlands) among patients aged 70 years or older attending the ED in 2012. Predictors were age, gender, time and way of arrival, presenting complaint, consulting medical specialty, vital signs, pain score and laboratory testing. Cox regression analyses were performed to analyse the association between these predictors and 90-day mortality. RESULTS: Three thousand two hundred one unique patients were eligible for inclusion. Ninety-day mortality was 10.5 % for the total group. Independent predictors of mortality were age (hazard ratio [HR] 1.06, 95 % confidence interval [95 % CI] 1.04-1.08), referral from another hospital (HR 2.74, 95 % CI 1.22-6.11), allocation to a non-surgical specialty (HR: 1.55, 95 % CI 1.13-2.14), increased respiration rate (HR up to 2.21, 95 % CI 1.25-3.92), low oxygen saturation (HR up to 1.96, 95 % CI 1.19-3.23), hypothermia (HR 2.27, 95 % CI 1.28-4.01), fever (HR 0.43, 95 % CI 0.24-0.75), high pain score (HR 1.55, 95 % CI 1.03-2.32) and the indication to perform laboratory testing (HR 3.44, 95 % CI 2.13-5.56). CONCLUSIONS: Routinely collected parameters at the ED can predict 90-day mortality in older patients presenting to the ED. This study forms the first step towards creating a new and simple screening tool to predict and improve health outcome in acutely presenting older patients.
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spelling pubmed-49444622016-07-15 Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study Hofman, Susanna E. Lucke, Jacinta A. Heim, Noor de Gelder, Jelle Fogteloo, Anne J. Heringhaus, Christian de Groot, Bas de Craen, Anton J. M. Blauw, Gerard Jan Mooijaart, Simon P. BMC Emerg Med Research Article BACKGROUND: Older people frequently attend the emergency department (ED) and have a high risk of poor outcome as compared to their younger counterparts. Our aim was to study routinely collected clinical parameters as predictors of 90-day mortality in older patients attending our ED. METHODS: We conducted a retrospective follow-up study at the Leiden University Medical Center (The Netherlands) among patients aged 70 years or older attending the ED in 2012. Predictors were age, gender, time and way of arrival, presenting complaint, consulting medical specialty, vital signs, pain score and laboratory testing. Cox regression analyses were performed to analyse the association between these predictors and 90-day mortality. RESULTS: Three thousand two hundred one unique patients were eligible for inclusion. Ninety-day mortality was 10.5 % for the total group. Independent predictors of mortality were age (hazard ratio [HR] 1.06, 95 % confidence interval [95 % CI] 1.04-1.08), referral from another hospital (HR 2.74, 95 % CI 1.22-6.11), allocation to a non-surgical specialty (HR: 1.55, 95 % CI 1.13-2.14), increased respiration rate (HR up to 2.21, 95 % CI 1.25-3.92), low oxygen saturation (HR up to 1.96, 95 % CI 1.19-3.23), hypothermia (HR 2.27, 95 % CI 1.28-4.01), fever (HR 0.43, 95 % CI 0.24-0.75), high pain score (HR 1.55, 95 % CI 1.03-2.32) and the indication to perform laboratory testing (HR 3.44, 95 % CI 2.13-5.56). CONCLUSIONS: Routinely collected parameters at the ED can predict 90-day mortality in older patients presenting to the ED. This study forms the first step towards creating a new and simple screening tool to predict and improve health outcome in acutely presenting older patients. BioMed Central 2016-07-13 /pmc/articles/PMC4944462/ /pubmed/27412243 http://dx.doi.org/10.1186/s12873-016-0090-5 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hofman, Susanna E.
Lucke, Jacinta A.
Heim, Noor
de Gelder, Jelle
Fogteloo, Anne J.
Heringhaus, Christian
de Groot, Bas
de Craen, Anton J. M.
Blauw, Gerard Jan
Mooijaart, Simon P.
Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study
title Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study
title_full Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study
title_fullStr Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study
title_full_unstemmed Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study
title_short Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study
title_sort prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944462/
https://www.ncbi.nlm.nih.gov/pubmed/27412243
http://dx.doi.org/10.1186/s12873-016-0090-5
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