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Incidence and prevalence of gout in Western Sweden

BACKGROUND: The aim of the present study was to describe prevalence and trends in the incidence of gout and patterns of urate-lowering treatment (ULT) in the Western Swedish Health Care Region (WSHCR) from 2002 to 2012. METHODS: We used regional and national healthcare registers to estimate the prev...

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Autores principales: Dehlin, Mats, Drivelegka, Panagiota, Sigurdardottir, Valgerdur, Svärd, Anna, Jacobsson, Lennart T. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944470/
https://www.ncbi.nlm.nih.gov/pubmed/27412614
http://dx.doi.org/10.1186/s13075-016-1062-6
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author Dehlin, Mats
Drivelegka, Panagiota
Sigurdardottir, Valgerdur
Svärd, Anna
Jacobsson, Lennart T. H.
author_facet Dehlin, Mats
Drivelegka, Panagiota
Sigurdardottir, Valgerdur
Svärd, Anna
Jacobsson, Lennart T. H.
author_sort Dehlin, Mats
collection PubMed
description BACKGROUND: The aim of the present study was to describe prevalence and trends in the incidence of gout and patterns of urate-lowering treatment (ULT) in the Western Swedish Health Care Region (WSHCR) from 2002 to 2012. METHODS: We used regional and national healthcare registers to estimate the prevalence and incidence of gout in 2012, and trends in incidence for each calendar year from 2005 to 2012. We also investigated the pattern of ULT for gout using the Swedish Prescribed Drug Register. RESULTS: In 2012, in the population aged 20 years and above, the prevalence of gout was 1.8 % (95 % confidence interval (CI) 1.77 to 1.82) and the incidence was 190 cases (95 % CI 180 to 200) per 100,000 person-years. Applying more strict definitions for a gout case rendered a prevalence of 1.36 % (95 % CI 1.34 to 1.38) and 0.5 (95 % CI 0.49 to 0.51) per 100,000 person-years, respectively. The incidence of gout increased steadily and significantly from 2005 to 2012, with an almost 50 % increase in the total population. There was no significant difference in the prevalence of gout in rural compared to urban areas. ULT was dispensed to only 42 % of patients with gout in 2012 who had ever been diagnosed with gout during the preceding 10-year period. CONCLUSIONS: Gout is the most common arthritic disease in WSHCR, Sweden, and has increased substantially over the last decade, with only a minority of prevalent cases in 2012 receiving ULT. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13075-016-1062-6) contains supplementary material, which is available to authorized users.
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spelling pubmed-49444702016-07-15 Incidence and prevalence of gout in Western Sweden Dehlin, Mats Drivelegka, Panagiota Sigurdardottir, Valgerdur Svärd, Anna Jacobsson, Lennart T. H. Arthritis Res Ther Research Article BACKGROUND: The aim of the present study was to describe prevalence and trends in the incidence of gout and patterns of urate-lowering treatment (ULT) in the Western Swedish Health Care Region (WSHCR) from 2002 to 2012. METHODS: We used regional and national healthcare registers to estimate the prevalence and incidence of gout in 2012, and trends in incidence for each calendar year from 2005 to 2012. We also investigated the pattern of ULT for gout using the Swedish Prescribed Drug Register. RESULTS: In 2012, in the population aged 20 years and above, the prevalence of gout was 1.8 % (95 % confidence interval (CI) 1.77 to 1.82) and the incidence was 190 cases (95 % CI 180 to 200) per 100,000 person-years. Applying more strict definitions for a gout case rendered a prevalence of 1.36 % (95 % CI 1.34 to 1.38) and 0.5 (95 % CI 0.49 to 0.51) per 100,000 person-years, respectively. The incidence of gout increased steadily and significantly from 2005 to 2012, with an almost 50 % increase in the total population. There was no significant difference in the prevalence of gout in rural compared to urban areas. ULT was dispensed to only 42 % of patients with gout in 2012 who had ever been diagnosed with gout during the preceding 10-year period. CONCLUSIONS: Gout is the most common arthritic disease in WSHCR, Sweden, and has increased substantially over the last decade, with only a minority of prevalent cases in 2012 receiving ULT. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13075-016-1062-6) contains supplementary material, which is available to authorized users. BioMed Central 2016-07-13 2016 /pmc/articles/PMC4944470/ /pubmed/27412614 http://dx.doi.org/10.1186/s13075-016-1062-6 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Dehlin, Mats
Drivelegka, Panagiota
Sigurdardottir, Valgerdur
Svärd, Anna
Jacobsson, Lennart T. H.
Incidence and prevalence of gout in Western Sweden
title Incidence and prevalence of gout in Western Sweden
title_full Incidence and prevalence of gout in Western Sweden
title_fullStr Incidence and prevalence of gout in Western Sweden
title_full_unstemmed Incidence and prevalence of gout in Western Sweden
title_short Incidence and prevalence of gout in Western Sweden
title_sort incidence and prevalence of gout in western sweden
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944470/
https://www.ncbi.nlm.nih.gov/pubmed/27412614
http://dx.doi.org/10.1186/s13075-016-1062-6
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