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SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer

BACKGROUND: To improve current treatment strategies for patients with aggressive colorectal cancer (CRC), the molecular understanding of subgroups of CRC with poor prognosis is of vast importance. SOX2 positive tumors have been associated with a poor patient outcome, but the functional role of SOX2...

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Detalles Bibliográficos
Autores principales:	Lundberg, Ida V., Edin, Sofia, Eklöf, Vincy, Öberg, Åke, Palmqvist, Richard, Wikberg, Maria L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944515/ https://www.ncbi.nlm.nih.gov/pubmed/27411517 http://dx.doi.org/10.1186/s12885-016-2509-5

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