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Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang

Acute myeloid leukemia (AML) is characterized by the accumulation of circulating immature blasts that exhibit uncontrolled growth, lack the ability to undergo normal differentiation, and have decreased sensitivity to apoptosis. Accumulating evidence shows the bone marrow (BM) niche is critical to th...

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Detalles Bibliográficos
Autores principales: Zhou, Hong-Sheng, Carter, Bing Z., Andreeff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944541/
https://www.ncbi.nlm.nih.gov/pubmed/27458532
http://dx.doi.org/10.20892/j.issn.2095-3941.2016.0023