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Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang
Acute myeloid leukemia (AML) is characterized by the accumulation of circulating immature blasts that exhibit uncontrolled growth, lack the ability to undergo normal differentiation, and have decreased sensitivity to apoptosis. Accumulating evidence shows the bone marrow (BM) niche is critical to th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Anti-Cancer Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944541/ https://www.ncbi.nlm.nih.gov/pubmed/27458532 http://dx.doi.org/10.20892/j.issn.2095-3941.2016.0023 |