MiR-31/SDHA Axis Regulates Reprogramming Efficiency through Mitochondrial Metabolism

Metabolism is remodeled when somatic cells are reprogrammed into induced pluripotent stem cells (iPSCs), but the majority of iPSCs are not fully reprogrammed. In a shift essential for reprogramming, iPSCs use less mitochondrial respiration but increased anaerobic glycolysis for bioenergetics. We fou...

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Detalles Bibliográficos
Autores principales: Lee, Man Ryul, Mantel, Charlie, Lee, Sang A., Moon, Sung-Hwan, Broxmeyer, Hal E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944586/
https://www.ncbi.nlm.nih.gov/pubmed/27346679
http://dx.doi.org/10.1016/j.stemcr.2016.05.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944586/
https://www.ncbi.nlm.nih.gov/pubmed/27346679
http://dx.doi.org/10.1016/j.stemcr.2016.05.012

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