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Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene?

OBJECTIVES: To evaluate the effect of immune failure and/or diabetes mellitus (DM) association on the mortality and morbidity of the Fournier's Gangrene (FG), and interrelatedly, the usability of HbA1c level in the prediction of prognosis. MATERIALS AND METHODS: The data of 38 patients with the...

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Autores principales: Sen, Haluk, Bayrak, Omer, Erturhan, Sakip, Borazan, Ersin, Koc, Mustafa Nihat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944629/
https://www.ncbi.nlm.nih.gov/pubmed/27453658
http://dx.doi.org/10.4103/0974-7796.184905
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author Sen, Haluk
Bayrak, Omer
Erturhan, Sakip
Borazan, Ersin
Koc, Mustafa Nihat
author_facet Sen, Haluk
Bayrak, Omer
Erturhan, Sakip
Borazan, Ersin
Koc, Mustafa Nihat
author_sort Sen, Haluk
collection PubMed
description OBJECTIVES: To evaluate the effect of immune failure and/or diabetes mellitus (DM) association on the mortality and morbidity of the Fournier's Gangrene (FG), and interrelatedly, the usability of HbA1c level in the prediction of prognosis. MATERIALS AND METHODS: The data of 38 patients with the diagnosis of FG were investigated retrospectively. The patients were divided into two groups as patients with DM (Group 1, n = 18) and non-diabetics (Group 2, n = 20). The patients in group 1 were also divided into two subgroups as patients with HbA1c value ≥7 (Group 1a) and HbA1c value <7 (Group 1b). RESULTS: The mean age of all 38 male patients was 66.3 ± 6.4 years. The initial symptoms were scrotal rash and swelling (n = 20, 52.6%), high fever (>38°C) (n = 22, 57.8%), purulent discharge from genital or perineal areas (n = 13, 34.2%), skin bruises (n = 11, 28.9%) and general state disorder in five patients that were admitted from day care center (13.1%). DM, as the most often comorbid disease, was detected in 18 patients (47.3%). Six patients (15.7%) were deceased during the follow-up period. CONCLUSION: In the present study, the researchers determined that diabetic patients with HbA1c level of 7 or higher had worse prognosis, and increased mortality.
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spelling pubmed-49446292016-07-22 Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene? Sen, Haluk Bayrak, Omer Erturhan, Sakip Borazan, Ersin Koc, Mustafa Nihat Urol Ann Original Article OBJECTIVES: To evaluate the effect of immune failure and/or diabetes mellitus (DM) association on the mortality and morbidity of the Fournier's Gangrene (FG), and interrelatedly, the usability of HbA1c level in the prediction of prognosis. MATERIALS AND METHODS: The data of 38 patients with the diagnosis of FG were investigated retrospectively. The patients were divided into two groups as patients with DM (Group 1, n = 18) and non-diabetics (Group 2, n = 20). The patients in group 1 were also divided into two subgroups as patients with HbA1c value ≥7 (Group 1a) and HbA1c value <7 (Group 1b). RESULTS: The mean age of all 38 male patients was 66.3 ± 6.4 years. The initial symptoms were scrotal rash and swelling (n = 20, 52.6%), high fever (>38°C) (n = 22, 57.8%), purulent discharge from genital or perineal areas (n = 13, 34.2%), skin bruises (n = 11, 28.9%) and general state disorder in five patients that were admitted from day care center (13.1%). DM, as the most often comorbid disease, was detected in 18 patients (47.3%). Six patients (15.7%) were deceased during the follow-up period. CONCLUSION: In the present study, the researchers determined that diabetic patients with HbA1c level of 7 or higher had worse prognosis, and increased mortality. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4944629/ /pubmed/27453658 http://dx.doi.org/10.4103/0974-7796.184905 Text en Copyright: © Urology Annals http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sen, Haluk
Bayrak, Omer
Erturhan, Sakip
Borazan, Ersin
Koc, Mustafa Nihat
Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene?
title Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene?
title_full Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene?
title_fullStr Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene?
title_full_unstemmed Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene?
title_short Is hemoglobin A1c level effective in predicting the prognosis of Fournier gangrene?
title_sort is hemoglobin a1c level effective in predicting the prognosis of fournier gangrene?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944629/
https://www.ncbi.nlm.nih.gov/pubmed/27453658
http://dx.doi.org/10.4103/0974-7796.184905
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