Cargando…
High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature
High-grade spindle cell sarcomas are rare undifferentiated pleomorphic cancers that present a treatment challenge to urological practices, especially when they present in the pelvis. We report a 46-year-old male patient who presented to our urology clinic with urinary retention after having a Foley...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944637/ https://www.ncbi.nlm.nih.gov/pubmed/27453666 http://dx.doi.org/10.4103/0974-7796.184907 |
_version_ | 1782442799585558528 |
---|---|
author | Agafonoff, Slava Vaidya, Shrikant K. DeFade, Brian |
author_facet | Agafonoff, Slava Vaidya, Shrikant K. DeFade, Brian |
author_sort | Agafonoff, Slava |
collection | PubMed |
description | High-grade spindle cell sarcomas are rare undifferentiated pleomorphic cancers that present a treatment challenge to urological practices, especially when they present in the pelvis. We report a 46-year-old male patient who presented to our urology clinic with urinary retention after having a Foley catheter placed at an outlying facility. A voiding trial was attempted, but the patient failed this trial. This failure resulted in cystoscopy with bilateral retrograde pyelograms, which revealed a compressed bladder due to extrinsic compression. This finding had been evaluated with a computed tomography (CT) scan with and without intravenous contrast that showed a 14 cm pelvic mass with bladder displacement and compression. A fine needle aspiration was done at this outlying facility, prior to referral to our office, and it confirmed spindle cell pathology. The mass was surgically excised with the histology revealing a pelvic spindle cell sarcoma with positive surgical margins. Further, metastatic work-up with CT/positron emission tomography revealed bone and lung metastasis. The patient is currently undergoing chemotherapy and radiation. In this case study, we will review staging, management, differential diagnosis, chemotherapy, and radiation. |
format | Online Article Text |
id | pubmed-4944637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-49446372016-07-22 High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature Agafonoff, Slava Vaidya, Shrikant K. DeFade, Brian Urol Ann Case Report High-grade spindle cell sarcomas are rare undifferentiated pleomorphic cancers that present a treatment challenge to urological practices, especially when they present in the pelvis. We report a 46-year-old male patient who presented to our urology clinic with urinary retention after having a Foley catheter placed at an outlying facility. A voiding trial was attempted, but the patient failed this trial. This failure resulted in cystoscopy with bilateral retrograde pyelograms, which revealed a compressed bladder due to extrinsic compression. This finding had been evaluated with a computed tomography (CT) scan with and without intravenous contrast that showed a 14 cm pelvic mass with bladder displacement and compression. A fine needle aspiration was done at this outlying facility, prior to referral to our office, and it confirmed spindle cell pathology. The mass was surgically excised with the histology revealing a pelvic spindle cell sarcoma with positive surgical margins. Further, metastatic work-up with CT/positron emission tomography revealed bone and lung metastasis. The patient is currently undergoing chemotherapy and radiation. In this case study, we will review staging, management, differential diagnosis, chemotherapy, and radiation. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4944637/ /pubmed/27453666 http://dx.doi.org/10.4103/0974-7796.184907 Text en Copyright: © Urology Annals http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Agafonoff, Slava Vaidya, Shrikant K. DeFade, Brian High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature |
title | High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature |
title_full | High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature |
title_fullStr | High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature |
title_full_unstemmed | High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature |
title_short | High-grade undifferentiated pleomorphic sarcoma of the pelvis: A case report and review of literature |
title_sort | high-grade undifferentiated pleomorphic sarcoma of the pelvis: a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944637/ https://www.ncbi.nlm.nih.gov/pubmed/27453666 http://dx.doi.org/10.4103/0974-7796.184907 |
work_keys_str_mv | AT agafonoffslava highgradeundifferentiatedpleomorphicsarcomaofthepelvisacasereportandreviewofliterature AT vaidyashrikantk highgradeundifferentiatedpleomorphicsarcomaofthepelvisacasereportandreviewofliterature AT defadebrian highgradeundifferentiatedpleomorphicsarcomaofthepelvisacasereportandreviewofliterature |