Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass

Understanding the molecular mechanisms that regulate β cell mass and proliferation is important for the treatment of diabetes. Here, we identified domperidone (DPD), a dopamine D2 receptor (DRD2) antagonist that enhances β cell mass. Over time, islet β cell loss occurs in dissociation cultures, and...

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Detalles Bibliográficos
Autores principales: Sakano, Daisuke, Choi, Sungik, Kataoka, Masateru, Shiraki, Nobuaki, Uesugi, Motonari, Kume, Kazuhiko, Kume, Shoen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944721/
https://www.ncbi.nlm.nih.gov/pubmed/27373926
http://dx.doi.org/10.1016/j.stemcr.2016.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944721/
https://www.ncbi.nlm.nih.gov/pubmed/27373926
http://dx.doi.org/10.1016/j.stemcr.2016.05.015

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