Cargando…
Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass
Understanding the molecular mechanisms that regulate β cell mass and proliferation is important for the treatment of diabetes. Here, we identified domperidone (DPD), a dopamine D2 receptor (DRD2) antagonist that enhances β cell mass. Over time, islet β cell loss occurs in dissociation cultures, and...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944721/ https://www.ncbi.nlm.nih.gov/pubmed/27373926 http://dx.doi.org/10.1016/j.stemcr.2016.05.015 |