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Retinoic Acid Is Sufficient for the In Vitro Induction of Mouse Spermatocytes

Meiosis is the key step in gametogenesis. However, the mechanism of mammalian meiosis remains poorly understood due to the lack of an in vitro model. Here, we report that retinoic acid (RA) is sufficient for inducing leptotene/zygotene spermatocytes from cultured mouse spermatogonial stem cells. Mul...

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Detalles Bibliográficos
Autores principales: Wang, Si, Wang, Xiuxia, Ma, Longfei, Lin, Xiwen, Zhang, Daoqin, Li, Zhen, Wu, Yujian, Zheng, Chunwei, Feng, Xue, Liao, Shangying, Feng, Yanmin, Chen, Jian, Hu, Xiangjing, Wang, Min, Han, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944723/
https://www.ncbi.nlm.nih.gov/pubmed/27346680
http://dx.doi.org/10.1016/j.stemcr.2016.05.013