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Biodegradable and Renal Clearable Inorganic Nanoparticles
Personalized treatment plans for cancer therapy have been at the forefront of oncology research for many years. With the advent of many novel nanoplatforms, this goal is closer to realization today than ever before. Inorganic nanoparticles hold immense potential in the field of nano‐oncology, but ha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944857/ https://www.ncbi.nlm.nih.gov/pubmed/27429897 http://dx.doi.org/10.1002/advs.201500223 |
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author | Ehlerding, Emily B. Chen, Feng Cai, Weibo |
author_facet | Ehlerding, Emily B. Chen, Feng Cai, Weibo |
author_sort | Ehlerding, Emily B. |
collection | PubMed |
description | Personalized treatment plans for cancer therapy have been at the forefront of oncology research for many years. With the advent of many novel nanoplatforms, this goal is closer to realization today than ever before. Inorganic nanoparticles hold immense potential in the field of nano‐oncology, but have considerable toxicity concerns that have limited their translation to date. In this review, an overview of emerging biologically safe inorganic nanoplatforms is provided, along with considerations of the challenges that need to be overcome for cancer theranostics with inorganic nanoparticles to become a reality. The clinical and preclinical studies of both biodegradable and renal clearable inorganic nanoparticles are discussed, along with their implications. |
format | Online Article Text |
id | pubmed-4944857 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-49448572016-07-14 Biodegradable and Renal Clearable Inorganic Nanoparticles Ehlerding, Emily B. Chen, Feng Cai, Weibo Adv Sci (Weinh) Progress Reports Personalized treatment plans for cancer therapy have been at the forefront of oncology research for many years. With the advent of many novel nanoplatforms, this goal is closer to realization today than ever before. Inorganic nanoparticles hold immense potential in the field of nano‐oncology, but have considerable toxicity concerns that have limited their translation to date. In this review, an overview of emerging biologically safe inorganic nanoplatforms is provided, along with considerations of the challenges that need to be overcome for cancer theranostics with inorganic nanoparticles to become a reality. The clinical and preclinical studies of both biodegradable and renal clearable inorganic nanoparticles are discussed, along with their implications. John Wiley and Sons Inc. 2015-10-27 /pmc/articles/PMC4944857/ /pubmed/27429897 http://dx.doi.org/10.1002/advs.201500223 Text en © 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Progress Reports Ehlerding, Emily B. Chen, Feng Cai, Weibo Biodegradable and Renal Clearable Inorganic Nanoparticles |
title | Biodegradable and Renal Clearable Inorganic Nanoparticles |
title_full | Biodegradable and Renal Clearable Inorganic Nanoparticles |
title_fullStr | Biodegradable and Renal Clearable Inorganic Nanoparticles |
title_full_unstemmed | Biodegradable and Renal Clearable Inorganic Nanoparticles |
title_short | Biodegradable and Renal Clearable Inorganic Nanoparticles |
title_sort | biodegradable and renal clearable inorganic nanoparticles |
topic | Progress Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944857/ https://www.ncbi.nlm.nih.gov/pubmed/27429897 http://dx.doi.org/10.1002/advs.201500223 |
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