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Biodegradable and Renal Clearable Inorganic Nanoparticles

Personalized treatment plans for cancer therapy have been at the forefront of oncology research for many years. With the advent of many novel nanoplatforms, this goal is closer to realization today than ever before. Inorganic nanoparticles hold immense potential in the field of nano‐oncology, but ha...

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Detalles Bibliográficos
Autores principales: Ehlerding, Emily B., Chen, Feng, Cai, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944857/
https://www.ncbi.nlm.nih.gov/pubmed/27429897
http://dx.doi.org/10.1002/advs.201500223
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author Ehlerding, Emily B.
Chen, Feng
Cai, Weibo
author_facet Ehlerding, Emily B.
Chen, Feng
Cai, Weibo
author_sort Ehlerding, Emily B.
collection PubMed
description Personalized treatment plans for cancer therapy have been at the forefront of oncology research for many years. With the advent of many novel nanoplatforms, this goal is closer to realization today than ever before. Inorganic nanoparticles hold immense potential in the field of nano‐oncology, but have considerable toxicity concerns that have limited their translation to date. In this review, an overview of emerging biologically safe inorganic nanoplatforms is provided, along with considerations of the challenges that need to be overcome for cancer theranostics with inorganic nanoparticles to become a reality. The clinical and preclinical studies of both biodegradable and renal clearable inorganic nanoparticles are discussed, along with their implications.
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spelling pubmed-49448572016-07-14 Biodegradable and Renal Clearable Inorganic Nanoparticles Ehlerding, Emily B. Chen, Feng Cai, Weibo Adv Sci (Weinh) Progress Reports Personalized treatment plans for cancer therapy have been at the forefront of oncology research for many years. With the advent of many novel nanoplatforms, this goal is closer to realization today than ever before. Inorganic nanoparticles hold immense potential in the field of nano‐oncology, but have considerable toxicity concerns that have limited their translation to date. In this review, an overview of emerging biologically safe inorganic nanoplatforms is provided, along with considerations of the challenges that need to be overcome for cancer theranostics with inorganic nanoparticles to become a reality. The clinical and preclinical studies of both biodegradable and renal clearable inorganic nanoparticles are discussed, along with their implications. John Wiley and Sons Inc. 2015-10-27 /pmc/articles/PMC4944857/ /pubmed/27429897 http://dx.doi.org/10.1002/advs.201500223 Text en © 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Progress Reports
Ehlerding, Emily B.
Chen, Feng
Cai, Weibo
Biodegradable and Renal Clearable Inorganic Nanoparticles
title Biodegradable and Renal Clearable Inorganic Nanoparticles
title_full Biodegradable and Renal Clearable Inorganic Nanoparticles
title_fullStr Biodegradable and Renal Clearable Inorganic Nanoparticles
title_full_unstemmed Biodegradable and Renal Clearable Inorganic Nanoparticles
title_short Biodegradable and Renal Clearable Inorganic Nanoparticles
title_sort biodegradable and renal clearable inorganic nanoparticles
topic Progress Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944857/
https://www.ncbi.nlm.nih.gov/pubmed/27429897
http://dx.doi.org/10.1002/advs.201500223
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