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Acyl lipidation of a peptide: effects on activity and epidermal permeability in vitro

Short-chain lipid conjugates can increase permeability of a small peptide across human epidermis; however, the emerging lipoaminoacid (LAA) conjugation technique is costly and can deliver mixed synthetic products of varied biological potential. LAA conjugation using a racemic mixture produces a mixt...

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Detalles Bibliográficos
Autores principales: Rocco, Daniel, Ross, James, Murray, Paul E, Caccetta, Rima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944909/
https://www.ncbi.nlm.nih.gov/pubmed/27468224
http://dx.doi.org/10.2147/DDDT.S104111