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Acyl lipidation of a peptide: effects on activity and epidermal permeability in vitro
Short-chain lipid conjugates can increase permeability of a small peptide across human epidermis; however, the emerging lipoaminoacid (LAA) conjugation technique is costly and can deliver mixed synthetic products of varied biological potential. LAA conjugation using a racemic mixture produces a mixt...
Autores principales: | Rocco, Daniel, Ross, James, Murray, Paul E, Caccetta, Rima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944909/ https://www.ncbi.nlm.nih.gov/pubmed/27468224 http://dx.doi.org/10.2147/DDDT.S104111 |
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