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Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome

Secreted factors of Staphylococcus aureus can activate host signaling from the epidermal growth factor receptor (EGFR). The superantigen toxic shock syndrome toxin-1 (TSST-1) contributes to mucosal cytokine production through a disintegrin and metalloproteinase (ADAM)-mediated shedding of EGFR ligan...

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Detalles Bibliográficos
Autores principales:	Breshears, Laura M., Gillman, Aaron N., Stach, Christopher S., Schlievert, Patrick M., Peterson, Marnie L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944920/ https://www.ncbi.nlm.nih.gov/pubmed/27414801 http://dx.doi.org/10.1371/journal.pone.0158969

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