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Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects

Cannabidiol (CBD) is a major Cannabis sativa constituent, which does not cause the typical marijuana psychoactivity. However, it has been shown to be active in a numerous pharmacological assays, including mice tests for anxiety, obsessive-compulsive disorder, depression and schizophrenia. In human t...

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Detalles Bibliográficos
Autores principales: Breuer, Aviva, Haj, Christeene G., Fogaça, Manoela V., Gomes, Felipe V., Silva, Nicole Rodrigues, Pedrazzi, João Francisco, Del Bel, Elaine A., Hallak, Jaime C., Crippa, José A., Zuardi, Antonio W., Mechoulam, Raphael, Guimarães, Francisco S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945002/
https://www.ncbi.nlm.nih.gov/pubmed/27416026
http://dx.doi.org/10.1371/journal.pone.0158779