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Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Fibroblastic reticular cells (FRCs) form the cellular scaffold of lymph nodes (LNs) and establish distinct microenvironmental niches to provide key molecules that drive innate and adaptive immune responses and control immune regulatory processes. Here, we have used a graph theory-based systems biolo...
Autores principales: | Novkovic, Mario, Onder, Lucas, Cupovic, Jovana, Abe, Jun, Bomze, David, Cremasco, Viviana, Scandella, Elke, Stein, Jens V., Bocharov, Gennady, Turley, Shannon J., Ludewig, Burkhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945005/ https://www.ncbi.nlm.nih.gov/pubmed/27415420 http://dx.doi.org/10.1371/journal.pbio.1002515 |
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