Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening

Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine important in normal and pathological biological processes. Newly synthesized pro-TNF-α is expressed on the plasma membrane and cleaved to release soluble TNF-α protein: both are biologically active. Secreted TNF-α signals through TNF...

Descripción completa

Detalles Bibliográficos
Autores principales: Udommethaporn, Sutthirat, Tencomnao, Tewin, McGowan, Eileen M., Boonyaratanakornkit, Viroj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945017/
https://www.ncbi.nlm.nih.gov/pubmed/27415000
http://dx.doi.org/10.1371/journal.pone.0159151

Ejemplares similares

Ejemplares similares