Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

OBJECTIVE: Mucosal-associated invariant T (MAIT) cells comprise a subpopulation of T cells that can be activated by bacterial products and cytokines to produce IFN-γ. Since little is known on MAIT cells during HCV infection, we compared their phenotype and function in comparison to HIV and HCV/HIV c...

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Detalles Bibliográficos
Autores principales: Spaan, Michelle, Hullegie, Sebastiaan J., Beudeker, Boris J. B., Kreefft, Kim, van Oord, Gertine W., Groothuismink, Zwier M. A., van Tilborg, Marjolein, Rijnders, Bart, de Knegt, Robert J., Claassen, Mark A. A., Boonstra, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945024/
https://www.ncbi.nlm.nih.gov/pubmed/27416100
http://dx.doi.org/10.1371/journal.pone.0159243

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