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Multiplex Detection of Rare Mutations by Picoliter Droplet Based Digital PCR: Sensitivity and Specificity Considerations
In cancer research, the accuracy of the technology used for biomarkers detection is remarkably important. In this context, digital PCR represents a highly sensitive and reproducible method that could serve as an appropriate tool for tumor mutational status analysis. In particular, droplet-based digi...
Autores principales: | Zonta, Eleonora, Garlan, Fanny, Pécuchet, Nicolas, Perez-Toralla, Karla, Caen, Ouriel, Milbury, Coren, Didelot, Audrey, Fabre, Elizabeth, Blons, Hélène, Laurent-Puig, Pierre, Taly, Valérie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945036/ https://www.ncbi.nlm.nih.gov/pubmed/27416070 http://dx.doi.org/10.1371/journal.pone.0159094 |
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