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Conditional knockout of polarity complex (atypical) PKCι reveals an anti-inflammatory function mediated by NF-κB

The conserved proteins of the polarity complex made up of atypical PKC (aPKC, isoforms ι and ζ), Par6, and Par3 determine asymmetry in several cell types, from Caenorhabditis elegans oocytes to vertebrate epithelia and neurons. We previously showed that aPKC is down-regulated in intestinal epithelia...

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Detalles Bibliográficos
Autores principales:	Forteza, Radia, Figueroa, Yolanda, Mashukova, Anastasia, Dulam, Vipin, Salas, Pedro J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945138/ https://www.ncbi.nlm.nih.gov/pubmed/27226486 http://dx.doi.org/10.1091/mbc.E16-02-0086

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