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Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1

The antagonism between cyclin-dependent kinases (Cdks) and the ubiquitin ligase APC/C-Cdh1 is central to eukaryotic cell cycle control. APC/C-Cdh1 targets cyclin B and other regulatory proteins for degradation, whereas Cdks disable APC/C-Cdh1 through phosphorylation of the Cdh1 activator protein at...

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Detalles Bibliográficos
Autores principales:	Höckner, Sebastian, Neumann-Arnold, Lea, Seufert, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945139/ https://www.ncbi.nlm.nih.gov/pubmed/27226481 http://dx.doi.org/10.1091/mbc.E15-11-0787

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