Cargando…
A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease
BACKGROUND/AIMS: With the recent progress in medical treatment, surgery still plays a necessary and important role in treating ulcerative colitis (UC) patients. In this study, we analyzed the surgical results and outcomes of UC in Taiwan in the recent 20 years, via a multi-center study through the c...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association for the Study of Intestinal Diseases
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945529/ https://www.ncbi.nlm.nih.gov/pubmed/27433147 http://dx.doi.org/10.5217/ir.2016.14.3.248 |
_version_ | 1782442885519507456 |
---|---|
author | Lin, Chun-Chi Wei, Shu-Chen Lin, Been-Ren Tsai, Wen-Sy Chen, Jinn-Shiun Hsu, Tzu-Chi Lin, Wei-Chen Huang, Tien-Yu Chao, Te-Hsin Lin, Hung-Hsin Wong, Jau-Min Lin, Jen-Kou |
author_facet | Lin, Chun-Chi Wei, Shu-Chen Lin, Been-Ren Tsai, Wen-Sy Chen, Jinn-Shiun Hsu, Tzu-Chi Lin, Wei-Chen Huang, Tien-Yu Chao, Te-Hsin Lin, Hung-Hsin Wong, Jau-Min Lin, Jen-Kou |
author_sort | Lin, Chun-Chi |
collection | PubMed |
description | BACKGROUND/AIMS: With the recent progress in medical treatment, surgery still plays a necessary and important role in treating ulcerative colitis (UC) patients. In this study, we analyzed the surgical results and outcomes of UC in Taiwan in the recent 20 years, via a multi-center study through the collaboration of Taiwan Society of IBD. METHODS: A retrospective analysis of surgery data of UC patients from January 1, 1995, through December 31, 2014, in 6 Taiwan major medical centers was conducted. The patients' demographic data, indications for surgery, and outcome details were recorded and analyzed. RESULTS: The data of 87 UC patients who received surgical treatment were recorded. The median post-operative follow-up duration was 51.1 months and ranged from 0.4 to 300 months. The mean age at UC diagnosis was 45.3±16.0 years and that at operation was 48.5±15.2 years. The 3 leading indications for surgical intervention were uncontrolled bleeding (16.1%), perforation (13.8%), and intractability (12.6%). In total, 27.6% of surgeries were performed in an emergency setting. Total or subtotal colectomy with rectal preservation (41.4%) was the most common operation. There were 6 mortalities, all due to sepsis. Emergency operation and low pre-operative albumin level were significantly associated with poor survival (P=0.013 and 0.034, respectively). CONCLUSIONS: In the past 20 years, there was no significant change in the indications for surgery in UC patients. Emergency surgeries and low pre-operative albumin level were associated with poor survival. Therefore, an optimal timing of elective surgery for people with poorly controlled UC is paramount. |
format | Online Article Text |
id | pubmed-4945529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Korean Association for the Study of Intestinal Diseases |
record_format | MEDLINE/PubMed |
spelling | pubmed-49455292016-07-18 A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease Lin, Chun-Chi Wei, Shu-Chen Lin, Been-Ren Tsai, Wen-Sy Chen, Jinn-Shiun Hsu, Tzu-Chi Lin, Wei-Chen Huang, Tien-Yu Chao, Te-Hsin Lin, Hung-Hsin Wong, Jau-Min Lin, Jen-Kou Intest Res Original Article BACKGROUND/AIMS: With the recent progress in medical treatment, surgery still plays a necessary and important role in treating ulcerative colitis (UC) patients. In this study, we analyzed the surgical results and outcomes of UC in Taiwan in the recent 20 years, via a multi-center study through the collaboration of Taiwan Society of IBD. METHODS: A retrospective analysis of surgery data of UC patients from January 1, 1995, through December 31, 2014, in 6 Taiwan major medical centers was conducted. The patients' demographic data, indications for surgery, and outcome details were recorded and analyzed. RESULTS: The data of 87 UC patients who received surgical treatment were recorded. The median post-operative follow-up duration was 51.1 months and ranged from 0.4 to 300 months. The mean age at UC diagnosis was 45.3±16.0 years and that at operation was 48.5±15.2 years. The 3 leading indications for surgical intervention were uncontrolled bleeding (16.1%), perforation (13.8%), and intractability (12.6%). In total, 27.6% of surgeries were performed in an emergency setting. Total or subtotal colectomy with rectal preservation (41.4%) was the most common operation. There were 6 mortalities, all due to sepsis. Emergency operation and low pre-operative albumin level were significantly associated with poor survival (P=0.013 and 0.034, respectively). CONCLUSIONS: In the past 20 years, there was no significant change in the indications for surgery in UC patients. Emergency surgeries and low pre-operative albumin level were associated with poor survival. Therefore, an optimal timing of elective surgery for people with poorly controlled UC is paramount. Korean Association for the Study of Intestinal Diseases 2016-07 2016-06-27 /pmc/articles/PMC4945529/ /pubmed/27433147 http://dx.doi.org/10.5217/ir.2016.14.3.248 Text en © Copyright 2016. Korean Association for the Study of Intestinal Diseases. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Lin, Chun-Chi Wei, Shu-Chen Lin, Been-Ren Tsai, Wen-Sy Chen, Jinn-Shiun Hsu, Tzu-Chi Lin, Wei-Chen Huang, Tien-Yu Chao, Te-Hsin Lin, Hung-Hsin Wong, Jau-Min Lin, Jen-Kou A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease |
title | A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease |
title_full | A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease |
title_fullStr | A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease |
title_full_unstemmed | A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease |
title_short | A retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in Taiwan: a study of Taiwan Society of Inflammatory Bowel Disease |
title_sort | retrospective analysis of 20-year data of the surgical management of ulcerative colitis patients in taiwan: a study of taiwan society of inflammatory bowel disease |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945529/ https://www.ncbi.nlm.nih.gov/pubmed/27433147 http://dx.doi.org/10.5217/ir.2016.14.3.248 |
work_keys_str_mv | AT linchunchi aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT weishuchen aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linbeenren aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT tsaiwensy aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT chenjinnshiun aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT hsutzuchi aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linweichen aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT huangtienyu aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT chaotehsin aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linhunghsin aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT wongjaumin aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linjenkou aretrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linchunchi retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT weishuchen retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linbeenren retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT tsaiwensy retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT chenjinnshiun retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT hsutzuchi retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linweichen retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT huangtienyu retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT chaotehsin retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linhunghsin retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT wongjaumin retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease AT linjenkou retrospectiveanalysisof20yeardataofthesurgicalmanagementofulcerativecolitispatientsintaiwanastudyoftaiwansocietyofinflammatoryboweldisease |