Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report

Changes in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a pat...

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Autores principales: Sturm, Dietrich, Schmidt-Wilcke, Tobias, Greiner, Tineke, Maier, Christoph, Schargus, Marc, Tegenthoff, Martin, Vorgerd, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945811/
https://www.ncbi.nlm.nih.gov/pubmed/27482195
http://dx.doi.org/10.1159/000446538
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author Sturm, Dietrich
Schmidt-Wilcke, Tobias
Greiner, Tineke
Maier, Christoph
Schargus, Marc
Tegenthoff, Martin
Vorgerd, Matthias
author_facet Sturm, Dietrich
Schmidt-Wilcke, Tobias
Greiner, Tineke
Maier, Christoph
Schargus, Marc
Tegenthoff, Martin
Vorgerd, Matthias
author_sort Sturm, Dietrich
collection PubMed
description Changes in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a patient suffering from neuropathy caused by AL amyloidosis and underlying multiple myeloma. Small-fiber damage was detected by CCM.
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spelling pubmed-49458112016-08-01 Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report Sturm, Dietrich Schmidt-Wilcke, Tobias Greiner, Tineke Maier, Christoph Schargus, Marc Tegenthoff, Martin Vorgerd, Matthias Case Rep Neurol Case Report Changes in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a patient suffering from neuropathy caused by AL amyloidosis and underlying multiple myeloma. Small-fiber damage was detected by CCM. S. Karger AG 2016-06-27 /pmc/articles/PMC4945811/ /pubmed/27482195 http://dx.doi.org/10.1159/000446538 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Sturm, Dietrich
Schmidt-Wilcke, Tobias
Greiner, Tineke
Maier, Christoph
Schargus, Marc
Tegenthoff, Martin
Vorgerd, Matthias
Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_full Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_fullStr Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_full_unstemmed Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_short Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report
title_sort confocal cornea microscopy detects involvement of corneal nerve fibers in a patient with light-chain amyloid neuropathy caused by multiple myeloma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945811/
https://www.ncbi.nlm.nih.gov/pubmed/27482195
http://dx.doi.org/10.1159/000446538
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