Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system

Myostatin (Mstn) is a conserved negative regulator of skeletal muscle mass in mammals. However, whether precise disruption of Mstn in livestock can be achieved and safely used to improve meat productivity has not been proven. We applied CRISPR/Cas9 system to generate Mstn knock-out (KO) rabbits and...

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Detalles Bibliográficos
Autores principales: Guo, Rihong, Wan, Yongjie, Xu, Dan, Cui, Libin, Deng, Mingtian, Zhang, Guomin, Jia, Ruoxin, Zhou, Wenjun, Wang, Zhen, Deng, Kaiping, Huang, Mingrui, Wang, Feng, Zhang, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945924/
https://www.ncbi.nlm.nih.gov/pubmed/27417210
http://dx.doi.org/10.1038/srep29855

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