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Mitochondrial cereblon functions as a Lon-type protease

Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix, and degrades oxidized and misfolded proteins, thereby protecting the cell from various extracellular stresses, including oxidative stress. The intellectual...

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Detalles Bibliográficos
Autores principales: Kataoka, Kosuke, Nakamura, China, Asahi, Toru, Sawamura, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945938/
https://www.ncbi.nlm.nih.gov/pubmed/27417535
http://dx.doi.org/10.1038/srep29986