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Noise processing by microRNA-mediated circuits: The Incoherent Feed-Forward Loop, revisited
The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably protein levels. The discovery of small non-coding RNAs (miRNAs) in specific motifs of the genetic regulatory network has...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946084/ https://www.ncbi.nlm.nih.gov/pubmed/27441269 http://dx.doi.org/10.1016/j.heliyon.2016.e00095 |