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The role of early detection and treatment in malaria elimination

Falciparum malaria persists in hard-to-reach areas or demographic groups that are missed by conventional healthcare systems but could be reached by trained community members in a malaria post (MP). The main focus of a MP is to provide uninterrupted and rapid access to rapid diagnostic tests (RDTs) a...

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Autores principales: Landier, Jordi, Parker, Daniel M., Thu, Aung Myint, Carrara, Verena I., Lwin, Khin Maung, Bonnington, Craig A., Pukrittayakamee, Sasithon, Delmas, Gilles, Nosten, François H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946177/
https://www.ncbi.nlm.nih.gov/pubmed/27421656
http://dx.doi.org/10.1186/s12936-016-1399-y
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author Landier, Jordi
Parker, Daniel M.
Thu, Aung Myint
Carrara, Verena I.
Lwin, Khin Maung
Bonnington, Craig A.
Pukrittayakamee, Sasithon
Delmas, Gilles
Nosten, François H.
author_facet Landier, Jordi
Parker, Daniel M.
Thu, Aung Myint
Carrara, Verena I.
Lwin, Khin Maung
Bonnington, Craig A.
Pukrittayakamee, Sasithon
Delmas, Gilles
Nosten, François H.
author_sort Landier, Jordi
collection PubMed
description Falciparum malaria persists in hard-to-reach areas or demographic groups that are missed by conventional healthcare systems but could be reached by trained community members in a malaria post (MP). The main focus of a MP is to provide uninterrupted and rapid access to rapid diagnostic tests (RDTs) and artemisinin-based combination therapy (ACT) too all inhabitants of a village. RDTs allow trained community members to perform malaria diagnosis accurately and prescribe appropriate treatment, reducing as much as possible any delay between the onset of fever and treatment. Early treatment with ACT and with a low-dose of primaquine prevents further transmission from human to mosquito. A functioning MP represents an essential component of any malaria elimination strategy. Implementing large-scale, high-coverage, community-based early diagnosis and treatment through MPs requires few technological innovations but relies on a very well structured organization able to train, supervise and supply MPs, to monitor activity and to perform strict malaria surveillance. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12936-016-1399-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-49461772016-07-16 The role of early detection and treatment in malaria elimination Landier, Jordi Parker, Daniel M. Thu, Aung Myint Carrara, Verena I. Lwin, Khin Maung Bonnington, Craig A. Pukrittayakamee, Sasithon Delmas, Gilles Nosten, François H. Malar J Review Falciparum malaria persists in hard-to-reach areas or demographic groups that are missed by conventional healthcare systems but could be reached by trained community members in a malaria post (MP). The main focus of a MP is to provide uninterrupted and rapid access to rapid diagnostic tests (RDTs) and artemisinin-based combination therapy (ACT) too all inhabitants of a village. RDTs allow trained community members to perform malaria diagnosis accurately and prescribe appropriate treatment, reducing as much as possible any delay between the onset of fever and treatment. Early treatment with ACT and with a low-dose of primaquine prevents further transmission from human to mosquito. A functioning MP represents an essential component of any malaria elimination strategy. Implementing large-scale, high-coverage, community-based early diagnosis and treatment through MPs requires few technological innovations but relies on a very well structured organization able to train, supervise and supply MPs, to monitor activity and to perform strict malaria surveillance. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12936-016-1399-y) contains supplementary material, which is available to authorized users. BioMed Central 2016-07-15 /pmc/articles/PMC4946177/ /pubmed/27421656 http://dx.doi.org/10.1186/s12936-016-1399-y Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Landier, Jordi
Parker, Daniel M.
Thu, Aung Myint
Carrara, Verena I.
Lwin, Khin Maung
Bonnington, Craig A.
Pukrittayakamee, Sasithon
Delmas, Gilles
Nosten, François H.
The role of early detection and treatment in malaria elimination
title The role of early detection and treatment in malaria elimination
title_full The role of early detection and treatment in malaria elimination
title_fullStr The role of early detection and treatment in malaria elimination
title_full_unstemmed The role of early detection and treatment in malaria elimination
title_short The role of early detection and treatment in malaria elimination
title_sort role of early detection and treatment in malaria elimination
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946177/
https://www.ncbi.nlm.nih.gov/pubmed/27421656
http://dx.doi.org/10.1186/s12936-016-1399-y
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