Lymphocytes influence intracranial aneurysm formation and rupture: role of extracellular matrix remodeling and phenotypic modulation of vascular smooth muscle cells

BACKGROUND: Intracranial aneurysms (IA) are increasingly recognized as a disease driven by chronic inflammation. Recent research has identified key mediators and processes underlying IA pathogenesis, but mechanistic understanding remains incomplete. Lymphocytic infiltrates have been demonstrated in...

Descripción completa

Detalles Bibliográficos
Autores principales: Sawyer, David M., Pace, Lauren A., Pascale, Crissey L., Kutchin, Alexander C., O’Neill, Brannan E., Starke, Robert M., Dumont, Aaron S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946206/
https://www.ncbi.nlm.nih.gov/pubmed/27416931
http://dx.doi.org/10.1186/s12974-016-0654-z

Ejemplares similares

Ejemplares similares