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Treatment of critically sized femoral defects with recombinant BMP-2 delivered by a modified mPEG-PLGA biodegradable thermosensitive hydrogel

BACKGROUND: Reconstruction of a segmental fracture with massive bone loss is still a challenge for orthopaedic surgeons. The aim of our study was to develop a suitable biodegradable thermosensitive hydrogel system as a carrier for bone morphogenetic protein (BMP)-2 delivery in the treatment of criti...

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Detalles Bibliográficos
Autores principales:	Peng, Kuo-Ti, Hsieh, Meng-Yow, Lin, Carl T., Chen, Chin-Fu, Lee, Mel S., Huang, Yi-You, Chang, Pey-Jium
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946224/ https://www.ncbi.nlm.nih.gov/pubmed/27421654 http://dx.doi.org/10.1186/s12891-016-1131-7

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