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Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo

Extracellular lysophosphatidate (LPA) is a potent bioactive lipid that signals through six G-protein-coupled receptors. This signaling is required for embryogenesis, tissue repair and remodeling processes. LPA is produced from circulating lysophosphatidylcholine by autotaxin (ATX), and is degraded o...

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Detalles Bibliográficos
Autores principales:	Benesch, Matthew G.K., Tang, Xiaoyun, Venkatraman, Ganesh, Bekele, Raie T., Brindley, David N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946318/ https://www.ncbi.nlm.nih.gov/pubmed/27533936 http://dx.doi.org/10.7555/JBR.30.20150058

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