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Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study

Rhodococcus equi is an unusual cause of infection in humans, but has emerged as an opportunistic pathogen among immunocompromised patients. Primary pulmonary involvement is the most common clinical presentation, although the spectrum of disease is broad. Diagnosing R. equi infections remains challen...

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Autores principales: Macken, Eline, de Jonge, Hylke, Van Caesbroeck, Daniël, Verhaegen, Jan, Van Kerkhoven, Dana, Van Wijngaerden, Eric, Kuypers, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946448/
https://www.ncbi.nlm.nih.gov/pubmed/27500216
http://dx.doi.org/10.1097/TXD.0000000000000519
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author Macken, Eline
de Jonge, Hylke
Van Caesbroeck, Daniël
Verhaegen, Jan
Van Kerkhoven, Dana
Van Wijngaerden, Eric
Kuypers, Dirk
author_facet Macken, Eline
de Jonge, Hylke
Van Caesbroeck, Daniël
Verhaegen, Jan
Van Kerkhoven, Dana
Van Wijngaerden, Eric
Kuypers, Dirk
author_sort Macken, Eline
collection PubMed
description Rhodococcus equi is an unusual cause of infection in humans, but has emerged as an opportunistic pathogen among immunocompromised patients. Primary pulmonary involvement is the most common clinical presentation, although the spectrum of disease is broad. Diagnosing R. equi infections remains challenging, both from clinical and microbiological view, and no standard treatment has been established. In this report, we present a detailed case of a 57-year-old male renal transplant recipient who developed R. equi bacteremia with a concomitant Pneumocystis jirovecii pneumonia. We describe the clinical features of R. equi infections, highlight the importance of an early diagnosis, and briefly review treatment options for this rare infection.
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spelling pubmed-49464482016-08-05 Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study Macken, Eline de Jonge, Hylke Van Caesbroeck, Daniël Verhaegen, Jan Van Kerkhoven, Dana Van Wijngaerden, Eric Kuypers, Dirk Transplant Direct Case Study Reports Rhodococcus equi is an unusual cause of infection in humans, but has emerged as an opportunistic pathogen among immunocompromised patients. Primary pulmonary involvement is the most common clinical presentation, although the spectrum of disease is broad. Diagnosing R. equi infections remains challenging, both from clinical and microbiological view, and no standard treatment has been established. In this report, we present a detailed case of a 57-year-old male renal transplant recipient who developed R. equi bacteremia with a concomitant Pneumocystis jirovecii pneumonia. We describe the clinical features of R. equi infections, highlight the importance of an early diagnosis, and briefly review treatment options for this rare infection. Lippincott Williams & Wilkins 2015-04-01 /pmc/articles/PMC4946448/ /pubmed/27500216 http://dx.doi.org/10.1097/TXD.0000000000000519 Text en Copyright © 2015 The Authors. Transplantation Direct. Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/3.0.
spellingShingle Case Study Reports
Macken, Eline
de Jonge, Hylke
Van Caesbroeck, Daniël
Verhaegen, Jan
Van Kerkhoven, Dana
Van Wijngaerden, Eric
Kuypers, Dirk
Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study
title Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study
title_full Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study
title_fullStr Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study
title_full_unstemmed Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study
title_short Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study
title_sort rhodococcus equi sepsis in a renal transplant recipient: a case study
topic Case Study Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946448/
https://www.ncbi.nlm.nih.gov/pubmed/27500216
http://dx.doi.org/10.1097/TXD.0000000000000519
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