Detection of Virus-Specific CD8+ T Cells With Cross-Reactivity Against Alloantigens: Potency and Flaws of Present Experimental Methods

Virus-specific T cells have the intrinsic capacity to cross-react against allogeneic HLA antigens, a phenomenon known as heterologous immunity. In transplantation, these cells may contribute to the alloimmune response and negatively impact graft outcome. This study describes the various techniques t...

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Detalles Bibliográficos
Autores principales: van den Heuvel, Heleen, Heutinck, Kirstin M., van der Meer-Prins, Ellen P.M.W., Yong, Si La, Claas, Frans H.J., ten Berge, Ineke J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Original Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946452/
https://www.ncbi.nlm.nih.gov/pubmed/27500209
http://dx.doi.org/10.1097/TXD.0000000000000550

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