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Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non‐small‐cell lung cancer cells

Recent discoveries have revealed that human cancer involves aberrant epigenetic alterations. We and others have previously shown that the histone methyltransferase EZH2, the catalytic subunit of polycomb repressive complex 2 (PRC2), is frequently overexpressed in non‐small‐cell lung cancer (NSCLC) a...

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Detalles Bibliográficos
Autores principales:	Takashina, Taichi, Kinoshita, Ichiro, Kikuchi, Junko, Shimizu, Yasushi, Sakakibara‐Konishi, Jun, Oizumi, Satoshi, Nishimura, Masaharu, Dosaka‐Akita, Hirotoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946723/ https://www.ncbi.nlm.nih.gov/pubmed/27116120 http://dx.doi.org/10.1111/cas.12957

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