Cargando…

Oxidation Protection in Metal-Binding Peptide Motif and Its Application to Antibody for Site-Selective Conjugation

Here, we demonstrate that a metal ion binding motif could serve as an efficient and robust tool for site-specific conjugation strategy. Cysteine-containing metal binding motifs were constructed as single repeat or tandem repeat peptides and their metal binding characteristics were investigated. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Chung, Hye-Shin, Lee, Sunbae, Park, Soon Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946781/
https://www.ncbi.nlm.nih.gov/pubmed/27420328
http://dx.doi.org/10.1371/journal.pone.0159451