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DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans

Mitochondrial dysfunction underlies numerous age-related pathologies. In an effort to uncover how the detrimental effects of mitochondrial dysfunction might be alleviated, we examined how the nematode C. elegans not only adapts to disruption of the mitochondrial electron transport chain, but in many...

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Detalles Bibliográficos
Autores principales:	Munkácsy, Erin, Khan, Maruf H., Lane, Rebecca K., Borror, Megan B., Park, Jae H., Bokov, Alex F., Fisher, Alfred L., Link, Christopher D., Rea, Shane L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946786/ https://www.ncbi.nlm.nih.gov/pubmed/27420916 http://dx.doi.org/10.1371/journal.pgen.1006133

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