The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair

The acetyltransferase Tip60/Kat5 acetylates both histone and non-histone proteins, and is involved in a variety of biological processes. By acetylating p53, Tip60 controls p53-dependent transcriptional activity and so is implicated as a tumor suppressor. However, many breast cancers with low Tip60 a...

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Detalles Bibliográficos
Autores principales: Bassi, C, Li, Y-T, Khu, K, Mateo, F, Baniasadi, P S, Elia, A, Mason, J, Stambolic, V, Pujana, M A, Mak, T W, Gorrini, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946888/
https://www.ncbi.nlm.nih.gov/pubmed/26915295
http://dx.doi.org/10.1038/cdd.2015.173

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