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Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders

Many postnatal onset neurological disorders such as autism spectrum disorders (ASDs) and intellectual disability are thought to arise largely from disruption of excitatory/inhibitory homeostasis. Although mouse models of Rett syndrome (RTT), a postnatal neurological disorder caused by loss-of-functi...

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Detalles Bibliográficos
Autores principales: Meng, Xiangling, Wang, Wei, Lu, Hui, He, Ling-jie, Chen, Wu, Chao, Eugene S, Fiorotto, Marta L, Tang, Bin, Herrera, Jose A, Seymour, Michelle L, Neul, Jeffrey L, Pereira, Fred A, Tang, Jianrong, Xue, Mingshan, Zoghbi, Huda Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946906/
https://www.ncbi.nlm.nih.gov/pubmed/27328325
http://dx.doi.org/10.7554/eLife.14199